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The organic anion transporter oat family

Webb1 aug. 2001 · Abstract The organic anion transporter (OAT) family handles a wide variety of clinically important compounds (antibiotics, nonsteriodal anti-inflammatory drugs, … Webb1 sep. 2009 · Organic anion transporters (Oats) are located in the barrier epithelia of diverse organs, where they mediate the absorption and excretion of a wide range of …

[PDF] Atp Dependent Organic Anion Transporters Advances In …

Webb多選択性有機アニオントランスポーターファミリー (OAT family)の同定と薬物輸送における役割の解析. 記事の概要. 抄録. 引用文献 (50) 著者関連情報. 共有する. 抄録. 薬物トラ … Webb23 juni 2000 · The OAT family represents mainly the renal secretory and reabsorptive pathway for organic anions and is also involved in the distribution of organic anion in the … china to give russia weapons https://thecoolfacemask.com

OATPs, OATs and OCTs: the organic anion and cation …

WebbOATs are multispecific organic anion transporters, the substrates of which include both endogenous (e.g. cyclic nucleotides, prostaglandins, urate, dicarboxylates) and … The organic anion transporter 1 (OAT1) also known as solute carrier family 22 member 6 (SLC22A6) is a protein that in humans is encoded by the SLC22A6 gene. It is a member of the organic anion transporter (OAT) family of proteins. OAT1 is a transmembrane protein that is expressed in the brain, the placenta, the eyes, smooth muscles, and the basolateral membrane of proximal tubular cells o… WebbGene Family The human SCL22 family of transporters encompasses at least 22 members with an additional six structurally related but not yet assigned genes. ... In Vitro and In … grampian emerald csc

The multispecific organic anion transporter (OAT) family

Category:The organic anion transporter (OAT) family: a systems biology ...

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The organic anion transporter oat family

Drug and toxicant handling by the OAT organic anion transporters …

Webb39 rader · 1 jan. 2015 · The organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 ... WebbBxPC-3 and MIA PaCa-2 pancreatic cancer cell lines were used to quantify transcripts of OATP 1B1 and 1B3. Results: OATP 1A2, 1B1, and 1B3 proteins were found ubiquitously …

The organic anion transporter oat family

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WebbMentioning: 17 - The aim of this study was to explore whether rhein could enhance the effects of pemetrexed (PTX) on the therapy of non-small-cell lung cancer (NSCLC) and to clarify the associated molecular mechanism. Our study shows that rhein in combination with PTX could obviously increase the systemic exposure of PTX in rats, which would be … Webb1 jan. 2015 · Abstract The organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal …

Webbscientific article WebbMany UTs and drugs administered to CKD patients are organic anions, which are physiologically eliminated by the organic anion transporter (OAT) system [6,7]. OATs …

WebbThe organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal of attention because of … WebbWe explored an atenolol transporter from among the cation or anion transporters. • OCT1 expressed on apical side in enterocytes has transport activity of atenolol. • Transport of …

Webb1 juni 2000 · Organic anion transporter (OAT) is an heterogenous family of negatively charged proteins, mainly located in kidneys and the liver, but OAT1/OAT3 are also found …

WebbSeveral families of multispecific organic anion and cation transporters, including OAT family transporters, have recently been identified by molecular cloning. The OAT family … grampian electrical solutionsWebb10 juli 2024 · Since, in the Oat3KO, the basolateral transport of organic anions by PT cells is dependent upon the remaining OAT (i.e., OAT1), treatment with probenecid should … grampian energy servicesWebb1 jan. 2015 · The organic anion transporter (OAT) subfamily, which constitutes roughly half of the SLC22 (solute carrier 22) transporter family, has received a great deal of attention … grampian eating disorder serviceWebb1 jan. 2006 · Organic anion transporter (OAT) family Gene name Protein name Tissue distribution Predominant substrates SLC22A6 OAT1 kidney PAH, PGE2, urate, NSAIDs, … china to gbp exchange rategrampian drug and alcohol serviceWebb9 juni 2010 · The mycotoxin, ochratoxin A (OTA), is thought to be responsible for Balkan endemic nephropathy. OTA accumulates in several tissues, especially in the kidneys and … grampian electricity supply companyWebbFör 1 dag sedan · Organic anion transporters 1 and 3 (OAT1/3) occupy a key role in mediating renal elimination. Kynurenic acid (KYNA) was previously discovered as an … china togetherness