Cisplatin pubmed

Author: jweg

August undefined, 2024

WebSep 15, 2024 · Cisplatin is the prototype platinum coordination complex classified as an … WebSep 18, 2024 · Cisplatin is a medication used to manage and treat solid tumors and hematologic malignancies. It is in the alkylating agent class of cytotoxic medications. This activity reviews the indications, action, and contraindications for cisplatinum as a valuable agent in treating malignancy.

Mitofusin2 ameliorated ER stress and mitochondrial ROS through ...

WebGemcitabine and cisplatin chemotherapy is an active combination in the treatment of platinum-resistant ovarian and peritoneal carcinoma Invest New Drugs. 2004 Nov;22 (4):475-80. doi: 10.1023/B:DRUG.0000036690.14585.a3. Authors Devansu Tewari 1 , Bradley J Monk , Mark Hunter , Camille A Falkner , Robert A Burger Affiliation WebCisplatin is a platinum chemotherapeutic used in a variety of malignancies. The … naked equity puts

cis-Diamminedichloroplatinum(II): effects of a …

WebAll studies in which mannitol was used for forced diuresis with cisplatin therapy were evaluated. Data synthesis: Cisplatin therapy can lead to transient and permanent renal impairment. Molecular and histologic changes occur … WebWe demonstrate that cisplatin-induced transition from epithelial to mesenchymal … WebNov 20, 2016 · Whole-exome sequencing or targeted exon-capture-based sequencing was performed on 180 tumors. Patients were categorized as cisplatin sensitive or cisplatin resistant by using a combination of postchemotherapy parameters, including serum tumor marker levels, radiology, and pathology at surgical resection of residual disease. medplaya riviera - adults only

Cisplatin: mode of cytotoxic action and molecular basis of resistance

Carboplatin versus cisplatin in solid tumors: an analysis of ... - PubMed

WebCisplatin is a widely used anti-cancer drug that is exceptionally effective against … WebFerroptosis had great potential to become a new approach in anti-tumor therapies and make up for some classic drugs, which open up a new way for their utility in clinic. Keywords: Cisplatin; Erastin; Ferroptosis; Glutathione; Glutathione … medplaya the agir springs hotelWebThirty-eight patients (33%) experienced grade 3 or 4 cisplatin related toxicities with 15 patients (12%) requiring significant dose modification. The reduced dose intensity in Study 99.06 improved tolerability. Incidence of significant late morbidity was low (6%). medplex bridgeport

"WebCisplatin or (SP-4-2)-diamminedichloridoplatinum(II) is one of the most potential and … " - Cisplatin pubmed

Cisplatin pubmed

WebAbstract Objectives: To determine the efficacy and toxicity of radiation therapy and concurrent weekly cisplatin chemotherapy in achieving a complete clinical and pathologic response when used for the primary treatment of locally-advanced vulvar carcinoma. WebCisplatin-resistant bladder cancer overexpresses particular sugar chains compared with chemotherapy-naïve bladder cancer. Using a recombinant protein from the malaria parasite Plasmodium falciparum, we can target these sugar chains, and our results showed a significant antitumor effect in cisplatin- …

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WebOct 20, 2003 · Abstract. Cisplatin is one of the most potent antitumor agents known, … WebMar 2, 2024 · Weekly Cisplatin Plus Radiation for Postoperative Head and Neck Cancer …

WebSep 3, 1991 · After a preliminary dose-finding study involving 12 patients with advanced or locally recurrent head and neck cancer, 27 patients were treated on a phase II protocol, using fluorouracil 350 mg/m2/d by continuous intravenous (IV) infusion over 5 days, followed on the sixth day by a 2-hour IV infusion … Web1. INTRODUCTION. Lung cancer has a high worldwide prevalence and is usually malignant, with the highest cancer‐related mortality. 1 , 2 Lung cancers can be grossly classified into non‐small cell lung carcinoma (NSCLC), accounting for about 85% of lung cancers, and small cell lung carcinoma, which is less prevalent. NSCLC can be further divided into …

WebFeb 5, 2024 · Cisplatin and Oxaliplatin: Our Current Understanding of Their Actions. … WebApr 14, 2024 · Among the extracellular vesicles, apoptotic bodies (ABs) are only formed during the apoptosis and perform a relevant role in the pathogenesis of different diseases. Recently, it has been demonstrated that ABs from human renal proximal tubular HK-2 cells, either induced by cisplatin or by UV light, can lead to further apoptotic death in …

WebCisplatin has dramatically improved the survival rate of cancer patients, but it has also …

WebCisplatin and MD-805 were loaded in the films by casting the polymer solution containing the drugs. Fractions of the drugs released from the PLA-CL films were governed by the initial loading, the film thickness, and the polymer molecular weight. The drug release profiles obeyed the classical Fickian diffusion equation at least in the early ... medplex obgyn clinicWebCisplatin is an effective chemotherapeutic agent for various solid tumours, but its use is limited by adverse effects in normal tissues. In particular, cisplatin is nephrotoxic and can cause acute kidney injury and chronic kidney disease. Preclinical studies have provided insights into the cellular … medplex couponWebCisplatin is a clinically advanced and highly effective anticancer drug used in the treatment of a wide variety of malignancies, such as head and neck, lung, testis, ovary, breast cancer, etc. medplex bh