Cisplatin binding protein
WebCisplatin is a chemotherapy drug which is used to treat cancers including: sarcoma, small cell lung cancer, germ cell tumors, lymphoma, and ovarian cancer. While it is often … WebAug 24, 2024 · Systematic Identification of Proteins Binding with Cisplatin in Blood by Affinity Chromatography and a Four-Dimensional Proteomic Method Authors: Jianmei Tao Shuailong Jia Huazhong University...
Cisplatin binding protein
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WebFull article: Insulin-like growth factor 2 mRNA-binding protein 2-stabilized long non-coding RNA Taurine up-regulated gene 1 (TUG1) promotes cisplatin-resistance of colorectal cancer via modulating autophagy Home All Journals Bioengineered List of Issues Volume 13, Issue 2 Insulin-like growth factor 2 mRNA-bindin .... Bioengineered WebCisplatin is a chemotherapy medication used to treat a number of cancers. [2] These include testicular cancer, ovarian cancer, cervical cancer, bladder cancer, head and neck cancer, esophageal cancer, lung cancer, …
WebJun 13, 2005 · Protein binding Cisplatin does not undergo instantaneous and reversible binding to plasma protein that is characteristic of normal drug-protein binding. However, the platinum itself is capable of binding to plasma proteins, including albumin, transferrin, and gamma globulin. WebCisplatin, cis - [PtCl 2 (NH 3) 2 ], is extensively used for the treatment of testicular and ovarian cancers and increasingly against other types of solid tumors (head/neck, lung, cervical, and bladder) ( 1 , 2 , 3 , 4 ). The cytotoxic effect of cisplatin is thought to be due to attack on DNA bases and induction of apoptosis in cancer cells ( 5 , 6
WebCisplatin is a platinum-based drug which acts by binding to DNA by forming intrastrand cross-link conjugate which eventually leads to apoptosis due to the activation of p53, … WebJun 3, 2013 · To identify proteins that bind to cisplatin, we synthesized two different platinum-agarose conjugates, one with two amino groups and another with two chlorides attached to platinum that are available for …
WebMay 26, 2024 · Using the fluorescent cisplatin analog BODIPY-cisplatin, two-dimensional gel electrophoresis, and mass spectrometry, we identified the protein binding partners in …
WebTherefore, the study is designed to investigate the regulatory function and mechanism of Taurine up-regulated gene 1 (TUG1) in the cisplatin resistance of CRC. qRT-PCR checked the expressions of TUG1, Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2), and miR-195-5p in CRC tissues and cells. how to search android phone for filesWebTherapeutic efficacy of cisplatin-based treatment of late stage urothelial carcinoma (UC) is limited by chemoresistance. To elucidate underlying mechanisms and to develop new approaches for overcoming resistance, we generated long-term cisplatin treated (LTT) UC cell lines, characterised their cisplatin response, and determined the expression of … how to search and count words in excelWebMar 27, 2024 · Cisplatin Relocalizes RNA Binding Protein HuR and Enhances the Oncolytic Activity of E4orf6 Deleted Adenovirus Cisplatin Relocalizes RNA Binding Protein HuR and Enhances the Oncolytic Activity of E4orf6 Deleted Adenovirus Cancers (Basel). 2024 Mar 27;12 (4):809. doi: 10.3390/cancers12040809. Authors how to search anonymously on googleWebJun 20, 2024 · Cisplatin [ cis- diamminedichloroplatinum (II) ( cis -DDP)] is one of the most successful anticancer agents effective against a wide range of solid tumors. However, its … how to search an image on cheggWebThe combination of adenoviruses and chemotherapy agents is a novel approach for human cancer therapeutics. A meticulous analysis between adenovirus and chemotherapeutic … how to search anonibWeb14 hours ago · The EV surface proteins as well as their expression in cells were analyzed with western blots. For the EV surface protein profiling, a coverslip coated with poly-l-lysine (PLL) to bind EVs and casein to reduce the unspecific binding of fluorescently tagged antibodies was used. The coverslip was probed with EVs and subsequently incubated … how to search an item by pictureWebMar 25, 2024 · Given that apoptosis resistance is one of the causes of the cisplatin resistance of tumor cells, our aim was to determine the relationship between RRS1 and cisplatin resistance in breast cancer cells. Here, we report that RRS1 is associated with cisplatin resistance in breast cancer cells. how to search anonymously